Alexander Disease MRI Severity and Clinical Staging

Stages Alexander disease using MRI white matter abnormality severity score, Rosenthal fiber distribution, bulbar/brainstem dysfunction severity, and seizure burden to guide supportive care planning

Each component has a specific meaning:

• Rosenthal fiber distribution — The rosenthal fiber distribution recorded for the scenario being assessed.
• Bulbar/brainstem dysfunction severity — The bulbar/brainstem dysfunction severity recorded for the scenario being assessed.
• Seizure burden — The seizure burden recorded for the scenario being assessed.

Note: Interpret the alexander disease stage result against the thresholds and context described above.

Enter the Rosenthal fiber distribution, bulbar/brainstem dysfunction severity, seizure burden for the scenario you are assessing. Stages Alexander disease using MRI white matter abnormality severity score, Rosenthal fiber distribution, bulbar/brainstem dysfunction severity, and seizure burden to guide supportive care planning. Use the alexander disease stage result to inform your calculation.