The Global APS Score (GAPSS) assigns points for hyperlipidemia (3), hypertension (1), aCL IgG/IgM (5), anti-β2GPI IgG/IgM (4), lupus anticoagulant (4), and anti-prothrombin antibodies (3). Higher scores predict recurrent thrombosis.

Which APS antibody profile carries highest risk?

Triple positivity (lupus anticoagulant + aCL + anti-β2GPI) carries the highest thrombotic risk. LA alone has higher thrombotic risk than isolated aCL or anti-β2GPI.

Antiphospholipid Syndrome Risk Score

Stratify thrombotic risk in antiphospholipid syndrome (APS) using the global APS score (GAPSS) or simplified APS risk stratification based on antibody profile and clinical history.

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Frequently Asked Questions

What is the GAPSS?

Which APS antibody profile carries highest risk?