ASPRE First-Trimester Preeclampsia Screening (sFlt-1/PlGF + MAP + UtA-PI)

Calculate first-trimester preeclampsia risk using the FMF ASPRE algorithm: MAP, uterine artery PI, PlGF, PAPP-A, and uterine history. Screen-positive women benefit from 150 mg aspirin started before 16 weeks to reduce early preeclampsia by 62%.

Weight
Height
Clinical Guidance

BMI is a screening measure of body size, not a direct measure of body fat. The standard WHO categories are underweight (<18.5), normal (18.5–24.9), overweight (25–29.9), and obese (≥30).

BMI can overestimate body fat in athletes with high muscle mass and underestimate it in older adults with low muscle mass. Interpret it alongside waist circumference and clinical context rather than as a standalone diagnosis.

⚕ Clinical Disclaimer: These calculators are for educational and reference purposes only. Always verify results with qualified clinical judgment and current clinical guidelines. Do not use as a sole basis for medical decisions.
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How It Works

Calculate first-trimester preeclampsia risk using the FMF ASPRE algorithm: MAP, uterine artery PI, PlGF, PAPP-A, and uterine history. Screen-positive women benefit from 150 mg aspirin started before 16 weeks to reduce early preeclampsia by 62%

Each component has a specific meaning:

  • FMF ASPRE algorithm: MAP — The fmf aspre algorithm: map recorded for the scenario being assessed.
  • Uterine artery PI — The uterine artery pi recorded for the scenario being assessed.
  • PlGF — The plgf recorded for the scenario being assessed.
  • PAPP-A — The papp-a recorded for the scenario being assessed.
  • Uterine history — The uterine history recorded for the scenario being assessed.

Note: Interpret the aspre pe screening result against the thresholds and context described above.

How to Use

Enter the FMF ASPRE algorithm: MAP, uterine artery PI, PlGF, PAPP-A, uterine history for the scenario you are assessing. Calculate first-trimester preeclampsia risk using the FMF ASPRE algorithm: MAP, uterine artery PI, PlGF, PAPP-A, and uterine history. Screen-positive women benefit from 150 mg aspirin started before 16 weeks to reduce early preeclampsia by 62%. Use the aspre pe screening result to inform your calculation.

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Frequently Asked Questions