How does Becker MD differ from Duchenne MD clinically?

Becker MD produces partially functional dystrophin (in-frame deletions), causing slower progression with ambulation typically preserved beyond age 15. Duchenne MD (out-of-frame mutations) causes loss of ambulation by age 12 in untreated patients.

Why is cardiac monitoring critical in Becker MD?

Dilated cardiomyopathy occurs in >70% of Becker MD patients and can develop even when skeletal muscle disease is mild. Annual echocardiography is recommended regardless of skeletal muscle severity; ACE inhibitors are started prophylactically.

Becker MD Severity Assessment

Evaluate Becker Muscular Dystrophy severity based on age of symptom onset, ambulation status, cardiac involvement, and serum CK levels.

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DMD Functional Score

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Becker MD Severity Assessment

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Frequently Asked Questions

How does Becker MD differ from Duchenne MD clinically?

Why is cardiac monitoring critical in Becker MD?