What do BILAG A–E grades mean?

A = severe disease requiring immunosuppression; B = moderate disease requiring treatment; C = mild stable disease; D = inactive disease (previously active); E = never active in this organ. Only A or B triggers treatment escalation.

How many organ systems does BILAG-2004 cover?

Nine: constitutional, mucocutaneous, neuropsychiatric, musculoskeletal, cardiorespiratory, gastrointestinal, ophthalmic, renal, and haematological.

When is BILAG preferred over SLEDAI?

BILAG is preferred in clinical trials requiring organ-specific activity assessment and treatment allocation. SLEDAI is preferred in routine clinical practice due to simplicity.

BILAG-2004 Lupus Organ-Based Activity Score

Apply the BILAG-2004 index to assess lupus disease activity across nine organ systems. Uses A-E grading per organ to guide therapeutic decisions, particularly for clinical trial enrollment.

⚕ Clinical Disclaimer: These calculators are for educational and reference purposes only. Always verify results with qualified clinical judgment and current clinical guidelines. Do not use as a sole basis for medical decisions.

How It Works

Apply the BILAG-2004 index to assess lupus disease activity across nine organ systems. Uses A-E grading per organ to guide therapeutic decisions, particularly for clinical trial enrollment

Each component has a specific meaning:

Nine organ systems — The nine organ systems recorded for the scenario being assessed.

Note: Interpret the bilag-2004 sle result against the thresholds and context described above.

How to Use

Enter the nine organ systems for the scenario you are assessing. Apply the BILAG-2004 index to assess lupus disease activity across nine organ systems. Uses A-E grading per organ to guide therapeutic decisions, particularly for clinical trial enrollment. Use the bilag-2004 sle result to inform your calculation.

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