What are the DAS28-CRP thresholds for disease activity?

DAS28-CRP 4.6 = high activity. These thresholds differ from DAS28-ESR as CRP and ESR have different normal distributions.

When is DAS28-CRP preferred over DAS28-ESR?

DAS28-CRP is preferred when ESR is unreliable — in elderly patients, chronic anemia, pregnancy, or hyperviscosity states where ESR may be chronically elevated regardless of RA activity.

DAS28-CRP — Rheumatoid Arthritis Disease Activity Score

Calculate the Disease Activity Score 28 using CRP (DAS28-CRP) to quantify rheumatoid arthritis disease activity, preferred in patients with chronically elevated ESR due to non-inflammatory causes.

Use the full interactive calculator below, or

DAS28-CRP — Rheumatoid Arthritis Disease Activity Score

Frequently Asked Questions

What are the DAS28-CRP thresholds for disease activity?

When is DAS28-CRP preferred over DAS28-ESR?