DOAC Reversal Agent Dosing Calculator (Idarucizumab/Andexanet)

Calculates idarucizumab (Praxbind) dosing for dabigatran reversal and andexanet alfa (Andexxa) dosing for apixaban/rivaroxaban/edoxaban reversal based on drug dose, last intake timing, and renal function.

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Clinical Guidance

BMI is a screening measure of body size, not a direct measure of body fat. The standard WHO categories are underweight (<18.5), normal (18.5–24.9), overweight (25–29.9), and obese (≥30).

BMI can overestimate body fat in athletes with high muscle mass and underestimate it in older adults with low muscle mass. Interpret it alongside waist circumference and clinical context rather than as a standalone diagnosis.

⚕ Clinical Disclaimer: These calculators are for educational and reference purposes only. Always verify results with qualified clinical judgment and current clinical guidelines. Do not use as a sole basis for medical decisions.
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How It Works

Calculates idarucizumab (Praxbind) dosing for dabigatran reversal and andexanet alfa (Andexxa) dosing for apixaban/rivaroxaban/edoxaban reversal based on drug dose, last intake timing, and renal function

Each component has a specific meaning:

  • Drug dose — The drug dose recorded for the scenario being assessed.
  • Last intake timing — The last intake timing recorded for the scenario being assessed.
  • Renal function — The renal function recorded for the scenario being assessed.

Note: Interpret the doac reversal dosing result against the thresholds and context described above.

How to Use

Enter the drug dose, last intake timing, renal function for the scenario you are assessing. Calculates idarucizumab (Praxbind) dosing for dabigatran reversal and andexanet alfa (Andexxa) dosing for apixaban/rivaroxaban/edoxaban reversal based on drug dose, last intake timing, and renal function. Use the doac reversal dosing result to inform your calculation.

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Frequently Asked Questions