What is the NSAA and how is it scored?

NSAA scores 17 functional items (standing, walking, climbing stairs, Gowers manoeuvre, etc.) each 0–2, giving 0–34 total. Items include a timed 10-metre walk and a timed rise from floor.

What NSAA trajectory is expected in untreated DMD?

Boys typically lose 1–2 NSAA points/year in the ambulatory phase. Loss of ambulation usually occurs when NSAA falls below 12–15 and mean age of ambulation loss is ~11–12 years without treatment.

North Star Ambulatory Assessment for Duchenne MD

Score the North Star Ambulatory Assessment (NSAA) in ambulatory Duchenne muscular dystrophy patients across 17 functional items to assess disease severity and monitor exon-skipping therapy response.

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North Star Ambulatory Assessment for Duchenne MD

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Frequently Asked Questions

What is the NSAA and how is it scored?

What NSAA trajectory is expected in untreated DMD?