FIB-4 Index — Liver Fibrosis Assessment

Calculate the FIB-4 Index using age, AST, ALT, and platelet count to non-invasively stage liver fibrosis and distinguish significant fibrosis (F2+) from minimal fibrosis in chronic liver disease.

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Clinical Guidance

BMI is a screening measure of body size, not a direct measure of body fat. The standard WHO categories are underweight (<18.5), normal (18.5–24.9), overweight (25–29.9), and obese (≥30).

BMI can overestimate body fat in athletes with high muscle mass and underestimate it in older adults with low muscle mass. Interpret it alongside waist circumference and clinical context rather than as a standalone diagnosis.

⚕ Clinical Disclaimer: These calculators are for educational and reference purposes only. Always verify results with qualified clinical judgment and current clinical guidelines. Do not use as a sole basis for medical decisions.
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How It Works

Calculate the FIB-4 Index using age, AST, ALT, and platelet count to non-invasively stage liver fibrosis and distinguish significant fibrosis (F2+) from minimal fibrosis in chronic liver disease

Each component has a specific meaning:

  • Age — The age recorded for the scenario being assessed.
  • AST — The ast recorded for the scenario being assessed.
  • ALT — The alt recorded for the scenario being assessed.
  • Platelet count — The platelet count recorded for the scenario being assessed.

Note: Interpret the fib-4 index result against the thresholds and context described above.

How to Use

Enter the age, AST, ALT, platelet count for the scenario you are assessing. Calculate the FIB-4 Index using age, AST, ALT, and platelet count to non-invasively stage liver fibrosis and distinguish significant fibrosis (F2+) from minimal fibrosis in chronic liver disease. Use the fib-4 index result to inform your calculation.

Frequently Asked Questions