How much does SVR from HCV treatment improve MELD?

Achieving SVR in HCV cirrhosis patients improves MELD by median 2–4 points over 12–24 months. Patients with MELD 20 rarely improves enough to delist from transplant waitlist.

Can antiviral therapy reverse HBV-related cirrhosis?

Prolonged HBV suppression (5–10 years) with tenofovir or entecavir can reduce Ishak fibrosis score by ≥1 stage in ~70–80% of patients and reverse some cirrhosis, especially in patients with compensated disease.

Viral Hepatitis Treatment Timing and MELD Impact Calculator

Calculate MELD improvement probability after antiviral therapy for HCV (DAA), HBV (nucleoside analogue), and HDV (peginterferon/bulevirtide), and estimate time to MELD improvement with treatment response data.

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Viral Hepatitis Treatment Timing and MELD Impact Calculator

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Frequently Asked Questions

How much does SVR from HCV treatment improve MELD?

Can antiviral therapy reverse HBV-related cirrhosis?