Hereditary Cardiomyopathy Genetic Risk Assessment

Assess pre-test probability and phenotype severity for hereditary cardiomyopathies (HCM, DCM, ARVC) based on gene variant type (sarcomere, desmosome, cytoskeletal), family history, and phenotype features.

Weight
Height
Clinical Guidance

BMI is a screening measure of body size, not a direct measure of body fat. The standard WHO categories are underweight (<18.5), normal (18.5–24.9), overweight (25–29.9), and obese (≥30).

BMI can overestimate body fat in athletes with high muscle mass and underestimate it in older adults with low muscle mass. Interpret it alongside waist circumference and clinical context rather than as a standalone diagnosis.

⚕ Clinical Disclaimer: These calculators are for educational and reference purposes only. Always verify results with qualified clinical judgment and current clinical guidelines. Do not use as a sole basis for medical decisions.
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How It Works

Assess pre-test probability and phenotype severity for hereditary cardiomyopathies (HCM, DCM, ARVC) based on gene variant type (sarcomere, desmosome, cytoskeletal), family history, and phenotype features

Each component has a specific meaning:

  • Gene variant type (sarcomere — The gene variant type (sarcomere recorded for the scenario being assessed.
  • Desmosome — The desmosome recorded for the scenario being assessed.
  • Cytoskeletal) — The cytoskeletal) recorded for the scenario being assessed.
  • Family history — The family history recorded for the scenario being assessed.
  • Phenotype features — The phenotype features recorded for the scenario being assessed.

Note: Interpret the cardiomyopathy genetic risk result against the thresholds and context described above.

How to Use

Enter the gene variant type (sarcomere, desmosome, cytoskeletal), family history, phenotype features for the scenario you are assessing. Assess pre-test probability and phenotype severity for hereditary cardiomyopathies (HCM, DCM, ARVC) based on gene variant type (sarcomere, desmosome, cytoskeletal), family history, and phenotype features. Use the cardiomyopathy genetic risk result to inform your calculation.

Frequently Asked Questions