What is the SPRS range and interpretation?

SPRS scores 0–52 across 13 items (gait, running, climbing stairs, spasticity, weakness, bladder, upper limb function). Scores ≤10 indicate mild, 11–30 moderate, >30 severe disability.

Which gene causes the most common form of HSP?

SPG4 (spastin gene, 2p22) accounts for 40% of autosomal dominant HSP. SPG3A (atlastin) and SPG31 (REEP1) are other common AD forms. SPG11 and SPG15 cause complex AR-HSP with thin corpus callosum.

SPRS — Spastic Paraplegia Rating Scale

Assess functional severity in hereditary spastic paraplegia (HSP) using the Spastic Paraplegia Rating Scale (SPRS) across upper and lower extremity spasticity, gait, bladder function, and pain domains.

Use the full interactive calculator below, or

SPRS — Spastic Paraplegia Rating Scale

Frequently Asked Questions

What is the SPRS range and interpretation?

Which gene causes the most common form of HSP?