Primary Hyperoxaluria Oxalate Burden Calculator

Calculates systemic oxalate burden in primary hyperoxaluria types 1-3 using 24-hour urinary oxalate, plasma oxalate, GFR, and estimates crystallization risk and lumasiran/oxalate lowering therapy response

Each component has a specific meaning:

• 24-hour urinary oxalate — The 24-hour urinary oxalate recorded for the scenario being assessed.
• Plasma oxalate — The plasma oxalate recorded for the scenario being assessed.
• GFR — The gfr recorded for the scenario being assessed.
• Estimates crystallization risk — The estimates crystallization risk recorded for the scenario being assessed.
• Lumasiran/oxalate lowering therapy response — The lumasiran/oxalate lowering therapy response recorded for the scenario being assessed.

Note: Interpret the ph oxalate burden result against the thresholds and context described above.

Enter the 24-hour urinary oxalate, plasma oxalate, GFR, estimates crystallization risk, lumasiran/oxalate lowering therapy response for the scenario you are assessing. Calculates systemic oxalate burden in primary hyperoxaluria types 1-3 using 24-hour urinary oxalate, plasma oxalate, GFR, and estimates crystallization risk and lumasiran/oxalate lowering therapy response. Use the ph oxalate burden result to inform your calculation.