King's College Criteria — Acetaminophen-Induced ALF

Apply the King's College Hospital criteria for acetaminophen (paracetamol)-induced acute liver failure to identify patients requiring urgent liver transplantation evaluation based on pH, lactate, coagulopathy, creatinine, and encephalopathy.

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Clinical Guidance

BMI is a screening measure of body size, not a direct measure of body fat. The standard WHO categories are underweight (<18.5), normal (18.5–24.9), overweight (25–29.9), and obese (≥30).

BMI can overestimate body fat in athletes with high muscle mass and underestimate it in older adults with low muscle mass. Interpret it alongside waist circumference and clinical context rather than as a standalone diagnosis.

⚕ Clinical Disclaimer: These calculators are for educational and reference purposes only. Always verify results with qualified clinical judgment and current clinical guidelines. Do not use as a sole basis for medical decisions.
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How It Works

Apply the King's College Hospital criteria for acetaminophen (paracetamol)-induced acute liver failure to identify patients requiring urgent liver transplantation evaluation based on pH, lactate, coagulopathy, creatinine, and encephalopathy

Each component has a specific meaning:

  • PH — The ph recorded for the scenario being assessed.
  • Lactate — The lactate recorded for the scenario being assessed.
  • Coagulopathy — The coagulopathy recorded for the scenario being assessed.
  • Creatinine — The creatinine recorded for the scenario being assessed.
  • Encephalopathy — The encephalopathy recorded for the scenario being assessed.

Note: Interpret the king's criteria paracetamol alf result against the thresholds and context described above.

How to Use

Enter the pH, lactate, coagulopathy, creatinine, encephalopathy for the scenario you are assessing. Apply the King's College Hospital criteria for acetaminophen (paracetamol)-induced acute liver failure to identify patients requiring urgent liver transplantation evaluation based on pH, lactate, coagulopathy, creatinine, and encephalopathy. Use the king's criteria paracetamol alf result to inform your calculation.

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