What is the minimum adequate Kt/V for hemodialysis?

KDOQI guidelines recommend spKt/V ≥1.2 per session for thrice-weekly hemodialysis. Values 1.3–1.4 are often targeted to provide a safety margin. Kt/V <1.2 is associated with excess hospitalization and mortality.

What is the Daugirdas second-generation formula?

spKt/V = -ln(R - 0.008t) + (4 - 3.5R) × (UF/W), where R = post-BUN/pre-BUN, t = treatment time in hours, UF = ultrafiltration in liters, W = post-dialysis weight in kg.

Kt/V Daugirdas — Dialysis Adequacy (Second Generation)

Calculate single-pool Kt/V dialysis adequacy using the Daugirdas second-generation formula from pre- and post-dialysis BUN, dialysis time, and ultrafiltration volume, targeting Kt/V ≥1.2 per session.

Use the full interactive calculator below, or

Kt/V Daugirdas — Dialysis Adequacy (Second Generation)

Frequently Asked Questions

What is the minimum adequate Kt/V for hemodialysis?

What is the Daugirdas second-generation formula?