What Lille score indicates corticosteroid failure?

Lille score >0.45 at day 7 predicts corticosteroid non-response with 6-month mortality >75% and mandates discontinuation of prednisolone to avoid immunosuppression without benefit.

What treatment options exist for Lille non-responders?

Options for steroid non-responders include pentoxifylline switch (limited evidence), liver transplantation in selected patients in specialized centers, or best supportive care in non-transplant candidates.

Lille Model — Corticosteroid Response in Alcoholic Hepatitis

Calculate the Lille Model score at day 7 of prednisolone therapy to assess treatment response in severe alcoholic hepatitis, with Lille >0.45 predicting non-response and 6-month mortality >75%.

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Lille Model — Corticosteroid Response in Alcoholic Hepatitis

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Frequently Asked Questions

What Lille score indicates corticosteroid failure?

What treatment options exist for Lille non-responders?