How does the Cooper nomogram predict lithium levels?

A 600 mg test dose is given and a level measured exactly 24 hours later. The Cooper nomogram uses this single level to predict the dose needed for target steady-state concentrations of 0.6–1.2 mEq/L.

What is the therapeutic range for lithium?

Acute mania: 0.8–1.2 mEq/L. Maintenance bipolar disorder: 0.6–0.8 mEq/L. Levels >1.5 mEq/L carry toxicity risk; >2.0 mEq/L indicate severe toxicity requiring hemodialysis consideration.

Lithium Cooper Nomogram — Steady-State Level Prediction

Use the Cooper lithium nomogram to predict steady-state lithium levels from a 24-hour test dose level, enabling initial dose selection without waiting for actual steady-state measurements.

Use the full interactive calculator below, or

Lithium Cooper Nomogram — Steady-State Level Prediction

Frequently Asked Questions

How does the Cooper nomogram predict lithium levels?

What is the therapeutic range for lithium?