What is the AREDS risk scoring system?

AREDS scale (0-4 per patient): 1 point for large drusen (>=125 microns) in each eye, 1 point for pigmentary abnormalities in each eye, minus 1 point if advanced AMD already present in one eye. Score 4: ~50% 5-year risk of advanced AMD.

When are AREDS2 supplements indicated?

AREDS2 supplements (vitamins C, E, lutein/zeaxanthin, zinc, copper) reduce risk of advanced AMD by ~25% in high-risk patients (AREDS categories 3-4 or advanced AMD in one eye). Not indicated for early AMD (few small drusen).

How has AREDS2 improved on AREDS?

AREDS2 replaced beta-carotene (lung cancer risk in smokers) with lutein/zeaxanthin. Zinc dose optimization evaluated. AREDS2 formulation is now recommended over original AREDS, especially in smokers or former smokers.

AMD Drusen Area AREDS Risk Score

Calculate AREDS risk score (0-4) for AMD progression to advanced AMD: large drusen >=125 microns (1pt/eye), pigment abnormalities (1pt/eye). Score predicts 5-year advanced AMD risk.

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AMD Drusen Area AREDS Risk Score

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Frequently Asked Questions

What is the AREDS risk scoring system?

When are AREDS2 supplements indicated?

How has AREDS2 improved on AREDS?