Calculates andexanet alfa dose for reversal of apixaban, rivaroxaban, and edoxaban in life-threatening bleeding. Low dose (400 mg IV bolus + 480 mg infusion over 2h): last apixaban ≤5 mg or rivaroxaban ≤10 mg, >8h since last dose. High dose (800 mg bolus + 960 mg infusion): all others.
Use the full interactive calculator below, or