What are the ARVC Task Force Criteria categories?

Six categories: structural/functional RV abnormality, histological characterization, repolarization abnormalities (T-wave inversions V1-V3), depolarization/conduction (epsilon wave, terminal activation duration), arrhythmia (LBBB-pattern VT), and family history/genetics.

How is ARVC classified by score?

Definite ARVC: 2 major, or 1 major + 2 minor, or 4 minor criteria. Borderline: 1 major + 1 minor, or 3 minor. Possible: 1 major or 2 minor criteria.

What genetic variants are major criteria?

Pathogenic variants in desmosomal genes (PKP2, DSG2, DSC2, DSP, JUP) or identification of a novel indeterminate variant in the context of Task Force positive family history constitute major genetic criteria.

ARVC Task Force Criteria Score

Score ARVC/ARLD using 2010 revised Task Force Criteria: structural, histological, repolarization, depolarization, arrhythmia, and family history/genetic criteria weighted as major/minor.

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