Which BCC subtype has highest recurrence risk?

Morpheaform/infiltrative (scar-like, ill-defined): 30-50% recurrence with standard excision. Micronodular (subclinical extension): 20-25%. Nodular: <5%. Superficial: <5%. These high-risk subtypes require Mohs or complete margin assessment.

What defines ulcus rodens BCC?

Ulcus rodens: deeply ulcerating BCC with destruction of underlying tissue (muscle, cartilage, bone). Seen in neglected or long-standing lesions. Despite local destruction, metastasis is very rare (<0.1%). Requires reconstructive surgery after clear margins.

When is vismodegib or sonidegib indicated for BCC?

Hedgehog pathway inhibitors (vismodegib, sonidegib) are indicated for locally advanced BCC not amenable to surgery, metastatic BCC, and Gorlin syndrome. Response rate 30-60% for locally advanced BCC but high discontinuation due to side effects.

BCC Ulcus Rodens vs Nodular Risk

Compare BCC subtypes: nodular (most common, low risk), superficial (low risk), morpheaform/infiltrative (high risk), and ulcus rodens (deeply infiltrative/ulcerated, very high risk) for recurrence and treatment approach.

Use the full interactive calculator below, or

BCC Ulcus Rodens vs Nodular Risk

Frequently Asked Questions

Which BCC subtype has highest recurrence risk?

What defines ulcus rodens BCC?

When is vismodegib or sonidegib indicated for BCC?