C3 Glomerulopathy Complement Profile

Evaluate C3 glomerulopathy using complement profile: low C3, normal C4, elevated C3 nephritic factor, and anti-CFH antibodies to guide eculizumab eligibility.

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Clinical Guidance

BMI is a screening measure of body size, not a direct measure of body fat. The standard WHO categories are underweight (<18.5), normal (18.5–24.9), overweight (25–29.9), and obese (≥30).

BMI can overestimate body fat in athletes with high muscle mass and underestimate it in older adults with low muscle mass. Interpret it alongside waist circumference and clinical context rather than as a standalone diagnosis.

⚕ Clinical Disclaimer: These calculators are for educational and reference purposes only. Always verify results with qualified clinical judgment and current clinical guidelines. Do not use as a sole basis for medical decisions.
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How It Works

Evaluate C3 glomerulopathy using complement profile: low C3, normal C4, elevated C3 nephritic factor, and anti-CFH antibodies to guide eculizumab eligibility

Each component has a specific meaning:

  • Complement profile: low C3 — The complement profile: low c3 recorded for the scenario being assessed.
  • Normal C4 — The normal c4 recorded for the scenario being assessed.
  • Elevated C3 nephritic factor — The elevated c3 nephritic factor recorded for the scenario being assessed.
  • Anti-CFH antibodies — The anti-cfh antibodies recorded for the scenario being assessed.

Note: Interpret the c3 glomerulopathy profile result against the thresholds and context described above.

How to Use

Enter the complement profile: low C3, normal C4, elevated C3 nephritic factor, anti-CFH antibodies for the scenario you are assessing. Evaluate C3 glomerulopathy using complement profile: low C3, normal C4, elevated C3 nephritic factor, and anti-CFH antibodies to guide eculizumab eligibility. Use the c3 glomerulopathy profile result to inform your calculation.

Frequently Asked Questions