What defines D'Amico intermediate risk?

Intermediate risk requires ALL of: PSA 10-20, Gleason score 7, and stage T2b - meaning any single intermediate-risk feature while meeting all low-risk criteria still classifies as intermediate.

How is the D'Amico classification used clinically?

Low risk: active surveillance or definitive monotherapy. Intermediate risk: definitive local therapy with or without short-term ADT. High risk: definitive therapy + 2-3 years ADT and consideration of pelvic nodal radiation.

D'Amico Prostate Cancer Risk Classification

Classify localised prostate cancer as Low, Intermediate, or High risk using PSA, Gleason score, and clinical stage. Low: PSA < 10 + GS <= 6 + stage <= T2a. High: PSA > 20 or GS >= 8 or stage >= T2c.

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Frequently Asked Questions

What defines D'Amico intermediate risk?

How is the D'Amico classification used clinically?