What are the RegiSCAR scoring parameters for DRESS?

RegiSCAR scores: hospitalization, reaction suspected drug-related, fever >38.5°C, lymphadenopathy ≥2 sites, skin rash >50% BSA, skin rash with ≥2 typical features, biopsy suggesting DRESS, organ involvement (liver/kidney/lung/muscle/cardiac), leukocyte abnormality (lymphocytosis, atypical lymphocytes, eosinophilia). Score ≥4 = definite DRESS.

Which drugs most commonly cause DRESS?

Aromatic anticonvulsants (carbamazepine, phenytoin, phenobarbital), allopurinol, sulfonamides, minocycline, abacavir, nevirapine, and lamotrigine. Onset is typically 2–8 weeks after drug initiation, distinguishing DRESS from urticaria or maculopapular exanthema.

DRESS Drug Reaction Severity Score (RegiSCAR)

Calculate the RegiSCAR score for DRESS/DIHS to classify cases as no case, possible, probable, or definite, integrating fever, lymphadenopathy, skin involvement, organ involvement, and eosinophilia.

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DRESS Drug Reaction Severity Score (RegiSCAR)

Frequently Asked Questions

What are the RegiSCAR scoring parameters for DRESS?

Which drugs most commonly cause DRESS?