What are the major Duke criteria for endocarditis?

Major criteria: (1) ≥2 separate positive blood cultures with typical IE organisms (S. viridans, S. bovis, HACEK, S. aureus, Enterococcus) or persistently positive cultures; (2) Evidence of endocardial involvement on echo (vegetation, abscess, new prosthetic valve dehiscence) or new valvular regurgitation.

Which organisms most commonly cause infective endocarditis?

Staphylococcus aureus is now the most common cause overall. Viridans streptococci are common in native valve IE. Coagulase-negative staphylococci and Enterococcus are frequent in prosthetic valve IE.

Infective Endocarditis Duke Criteria

Diagnoses infective endocarditis using major criteria (≥2 positive blood cultures with typical organisms, new valvular regurgitation or echo vegetation) and minor criteria (predisposing heart condition, IV drug use, fever >38°C, vascular phenomena, immunologic phenomena). Definite: 2 major OR 1 major+3 minor OR 5 minor.

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Infective Endocarditis Duke Criteria

Frequently Asked Questions

What are the major Duke criteria for endocarditis?

Which organisms most commonly cause infective endocarditis?