EEsAI scores solid food dysphagia (0–25 based on frequency and food texture), liquid dysphagia, pain, and avoidance behaviors (eating slowly, cutting small pieces, drinking during meals). Total 0–100. Score ≤20 indicates symptom remission. Correlates moderately with endoscopic and histologic scores.

What is the relationship between symptoms and histology in EoE?

Symptom scores and histology correlate only moderately (r ~0.4). Histologic remission (≤15 eos/hpf) can occur without symptom resolution (due to fibrostenosis) and symptom improvement without histologic remission can occur. Both endpoints are now required in clinical trials.

Eosinophilic Esophagitis Symptom Score (EEsAI)

Calculate the Eosinophilic Esophagitis Activity Index (EEsAI) scoring dysphagia frequency, dietary modification, and avoidance behaviors to measure treatment response and disease activity.

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Eosinophilic Esophagitis Symptom Score (EEsAI)

Frequently Asked Questions

How is EEsAI scored?

What is the relationship between symptoms and histology in EoE?