What are the major causes of erythroderma?

Psoriasis (25%), eczema (20%), drug reactions (15%), CTCL/Sézary syndrome (10%), pityriasis rubra pilaris, pemphigus foliaceus, and idiopathic (30%). Workup includes skin biopsy, peripheral blood flow cytometry (CD4:CD8 ratio), and staging for malignancy.

What systemic complications occur in erythroderma?

Thermoregulatory failure (hypothermia via massive heat loss), high-output cardiac failure, hypoalbuminemia/edema from protein loss through skin, fluid/electrolyte imbalance, infection (cellulitis, sepsis), and drug toxicity from altered drug absorption through inflamed skin.

Erythroderma Severity Assessment

Assess severity of erythroderma (>90% BSA erythema) by scoring systemic involvement including thermoregulatory failure, cardiac burden, hypoalbuminemia, and lymphadenopathy.

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Erythroderma Severity Assessment

Frequently Asked Questions

What are the major causes of erythroderma?

What systemic complications occur in erythroderma?