How is the furosemide stress test performed?

Administer furosemide 1.0 mg/kg IV (1.5 mg/kg if prior furosemide exposure) after correcting hypovolemia. Measure urine output hours 1-2. UO <200 mL in 2 hours predicts AKI progression to KDIGO stage 3 (AUROC ~0.87).

What is the advantage of FST over biomarkers?

FST directly tests tubular functional reserve rather than injury markers. It provides dynamic information about tubular function with superior predictive value for KDIGO stage 3 AKI.

Can FST guide RRT timing?

Yes. Poor FST response (UO <200 mL/2h) combined with KDIGO stage 2-3 AKI may support earlier RRT initiation. FST also identifies patients likely to recover without RRT.

Furosemide Stress Test Response Threshold

Use furosemide stress test (FST) to assess tubular integrity in AKI. Urine output <200 mL in first 2 hours after furosemide 1 mg/kg predicts KDIGO stage 3 AKI progression.

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Furosemide Stress Test Response Threshold

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Frequently Asked Questions

How is the furosemide stress test performed?

What is the advantage of FST over biomarkers?

Can FST guide RRT timing?