How do ASE and ESC models differ?

ESC HCM Risk-SCD calculates a continuous 5-year risk score using 7 variables. ASE uses a major risk factor approach (resuscitated VF, spontaneous sustained VT, family SCD, unexplained syncope, NSVT, abnormal BP response, max wall thickness >=30mm).

Which model is more widely validated?

ESC Risk-SCD has extensive validation in over 3,600 patients. ASE model has broader use in North America. Both are recommended to be used together when results are discordant.

At what ESC score is ICD recommended?

ESC recommends ICD consideration when 5-year risk >=6% (high risk). ICD may be considered at 4-6% (intermediate) based on clinical judgment and shared decision-making.

HCM SCD Risk ASE/ESC Model Comparison

Compare ASE and ESC risk stratification models for sudden cardiac death in hypertrophic cardiomyopathy. ESC uses continuous HCM Risk-SCD score; ASE uses major/modifier risk factor counting.

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