How is ICU-acquired weakness diagnosed?

ICUAW defined as MRC sum score =-1). Occurs in 33 to 56% of patients on MV >4 days. Increases ICU LOS, 1-year mortality, and long-term disability.

What are modifiable risk factors for ICU-acquired weakness?

Modifiable: immobilization (early physiotherapy reduces ICUAW risk 40 to 50%), deep sedation (daily SAT target RASS -2 to 0), corticosteroids (high-dose, prolonged), neuromuscular blockers (unavoidable in ARDS - use <=48h), hyperglycemia (intensive insulin targeting 140 to 180 mg/dL reduces ICUAW), parenteral nutrition within 48h.

ICU-Acquired Weakness Likelihood Assessment

Assess likelihood of ICU-acquired weakness (ICUAW) using MRC sum score of 6 bilateral muscle groups and identify modifiable risk factors including duration of immobility, corticosteroids, and hyperglycemia.

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Frequently Asked Questions

How is ICU-acquired weakness diagnosed?

What are modifiable risk factors for ICU-acquired weakness?