What is the indomethacin dose for PDA closure?

Standard course: 0.1 mg/kg IV q12h x3 doses for age less than 48 hours; 0.2 mg/kg initial then 0.1 mg/kg for 2–7 days; 0.2 mg/kg x3 doses for age over 7 days. Administer over 20–30 minutes.

What monitoring is required during indomethacin therapy?

Monitor renal function (urine output, creatinine, BUN), platelet count, and coagulation. Hold if urine output falls below 0.6 mL/kg/hour. Avoid concomitant aminoglycosides during treatment.

Indomethacin PDA Dose (Neonatal)

Calculate indomethacin dosing regimen for pharmacologic closure of patent ductus arteriosus in preterm neonates, with age-stratified dosing and renal monitoring intervals.

⚕ Clinical Disclaimer: These calculators are for educational and reference purposes only. Always verify results with qualified clinical judgment and current clinical guidelines. Do not use as a sole basis for medical decisions.

How to Use

Enter the values for the scenario you are assessing. Calculate indomethacin dosing regimen for pharmacologic closure of patent ductus arteriosus in preterm neonates, with age-stratified dosing and renal monitoring intervals. Use the indomethacin pda result to inform your calculation.

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