Irinotecan UGT1A1 Toxicity Grade Calculator

Predict irinotecan grade 3-4 diarrhea and neutropenia severity from UGT1A1 *28 promoter polymorphism status.

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Clinical Guidance

BMI is a screening measure of body size, not a direct measure of body fat. The standard WHO categories are underweight (<18.5), normal (18.5–24.9), overweight (25–29.9), and obese (≥30).

BMI can overestimate body fat in athletes with high muscle mass and underestimate it in older adults with low muscle mass. Interpret it alongside waist circumference and clinical context rather than as a standalone diagnosis.

⚕ Clinical Disclaimer: These calculators are for educational and reference purposes only. Always verify results with qualified clinical judgment and current clinical guidelines. Do not use as a sole basis for medical decisions.
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How It Works

Predict irinotecan grade 3-4 diarrhea and neutropenia severity from UGT1A1 *28 promoter polymorphism status

Each component has a specific meaning:

  • UGT1A1 *28 promoter polymorphism status — The ugt1a1 *28 promoter polymorphism status recorded for the scenario being assessed.

Note: Interpret the irinotecan ugt1a1 result against the thresholds and context described above.

How to Use

Enter the UGT1A1 *28 promoter polymorphism status for the scenario you are assessing. Predict irinotecan grade 3-4 diarrhea and neutropenia severity from UGT1A1 *28 promoter polymorphism status. Use the irinotecan ugt1a1 result to inform your calculation.

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