How does Lugano differ from Ann Arbor staging for lymphoma?

Lugano 2014 replaces bone marrow biopsy with PET-CT for FDG-avid lymphomas in initial staging and response assessment. It defines CR as Deauville 1–3 without new lesions. Ann Arbor Stage I–IV remains the anatomic backbone but PET-CT drives treatment decisions.

What defines bulky disease in Hodgkin lymphoma?

Lugano defines bulky as a single nodal mass 10 cm or more in diameter (Lugano 10 cm rule) or mediastinal tumor ratio (MTR) above one-third of thoracic diameter (MTR method). Bulky disease requires radiation consolidation in early-stage HL after chemotherapy.

Lugano Staging for Hodgkin Lymphoma

Apply Lugano 2014 classification for Hodgkin and non-Hodgkin lymphoma staging using PET-CT, replacing Ann Arbor staging for response assessment and incorporating Deauville criteria.

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Lugano Staging for Hodgkin Lymphoma

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Frequently Asked Questions

How does Lugano differ from Ann Arbor staging for lymphoma?

What defines bulky disease in Hodgkin lymphoma?