Lyme Disease Clinical Staging

Classifies Lyme disease into three stages: (1) Early localized — erythema migrans, single lesion, 3–30 days post-tick bite; (2) Early disseminated — multiple EM, carditis, facial palsy, meningitis, days to weeks post-bite; (3) Late disseminated — Lyme arthritis, encephalopathy, months to years post-bite.