How is CNVM classified in AMD?

Classic CNVM: well-defined fluorescein leakage in early FA phase, typically better prognosis with treatment. Occult CNVM: late ill-defined leakage or fibrovascular PED. Mixed: both components. OCT-angiography allows non-invasive CNVM visualization without dye.

What is the significance of subfoveal CNVM location?

Subfoveal CNVM (under foveal center) is the most vision-threatening location. Before anti-VEGF, thermal laser was contraindicated subfoveally. Anti-VEGF is first-line regardless of CNVM location and subfoveal extension.

What OCT features indicate active CNVM?

Active CNVM OCT features: subretinal fluid (SRF), intraretinal fluid (IRF), sub-RPE fluid, and inner segment/outer segment disruption. SRF alone may be tolerated in treat-and-extend; IRF typically requires treatment.

Macular Degeneration CNVM Size Threshold

Assess choroidal neovascularization membrane (CNVM) size and type in neovascular AMD. Classic CNVM >=4 disc areas or occult CNVM with recent progression are key treatment thresholds.

⚕ Clinical Disclaimer: These calculators are for educational and reference purposes only. Always verify results with qualified clinical judgment and current clinical guidelines. Do not use as a sole basis for medical decisions.

How to Use

Enter the values for the scenario you are assessing. Assess choroidal neovascularization membrane (CNVM) size and type in neovascular AMD. Classic CNVM >=4 disc areas or occult CNVM with recent progression are key treatment thresholds. Use the cnvm size threshold result to inform your calculation.

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