Seizure prophylaxis in severe preeclampsia: Loading dose 4 g IV over 15–20 minutes, then maintenance 1–2 g/hr continuous infusion. Monitor for toxicity: loss of patellar reflexes (8–12 mg/dL) → respiratory depression (12–16 mg/dL) → cardiac arrest (>15 mg/dL). Antidote: calcium gluconate 1 g IV.
Use the full interactive calculator below, or