Calculates mannitol dosing for elevated intracranial pressure (ICP). Dose: 0.25–1 g/kg IV over 20 minutes; repeat every 4–6 hours as needed. Hold if serum osmolality >320 mOsm/kg or serum sodium >155 mEq/L (risk of renal failure and rebound ICP). Use 20% or 25% mannitol solution. Foley catheter required. Monitor serum electrolytes and osmolality every 4–6 hours.
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