Mastocytosis Mast Cell Burden Score

Assess mast cell burden in systemic mastocytosis using serum tryptase level, bone marrow mast cell percentage, and WHO B and C findings to classify indolent vs advanced disease.

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Clinical Guidance

BMI is a screening measure of body size, not a direct measure of body fat. The standard WHO categories are underweight (<18.5), normal (18.5–24.9), overweight (25–29.9), and obese (≥30).

BMI can overestimate body fat in athletes with high muscle mass and underestimate it in older adults with low muscle mass. Interpret it alongside waist circumference and clinical context rather than as a standalone diagnosis.

⚕ Clinical Disclaimer: These calculators are for educational and reference purposes only. Always verify results with qualified clinical judgment and current clinical guidelines. Do not use as a sole basis for medical decisions.
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How It Works

Assess mast cell burden in systemic mastocytosis using serum tryptase level, bone marrow mast cell percentage, and WHO B and C findings to classify indolent vs advanced disease

Each component has a specific meaning:

  • Serum tryptase level — The serum tryptase level recorded for the scenario being assessed.
  • Bone marrow mast cell percentage — The bone marrow mast cell percentage recorded for the scenario being assessed.
  • WHO B — The who b recorded for the scenario being assessed.
  • C findings — The c findings recorded for the scenario being assessed.

Note: Interpret the mastocytosis burden result against the thresholds and context described above.

How to Use

Enter the serum tryptase level, bone marrow mast cell percentage, WHO B, C findings for the scenario you are assessing. Assess mast cell burden in systemic mastocytosis using serum tryptase level, bone marrow mast cell percentage, and WHO B and C findings to classify indolent vs advanced disease. Use the mastocytosis burden result to inform your calculation.

Frequently Asked Questions