How is MELD score calculated?

MELD = 6.43 + 9.57 x ln(creatinine mg/dL) + 3.78 x ln(bilirubin mg/dL) + 11.2 x ln(INR). Minimum value for each variable is 1.0 (to avoid negative scores). Maximum creatinine capped at 4.0 mg/dL.

What MELD score predicts 90-day mortality?

MELD 10: 4-6% 90-day mortality. MELD 20: 20-25%. MELD 30: 52-57%. MELD 40+: > 70%. MELD >= 15 is the threshold where transplant survival benefit typically exceeds survival on the waiting list.

What is the difference between MELD and MELD-Na?

MELD-Na adds serum sodium to account for hyponatraemia, which independently predicts waitlist mortality. MELD-Na has been used by UNOS since 2016 for transplant allocation.

MELD Score (Model for End-Stage Liver Disease)

Calculate MELD score for liver disease severity and transplant prioritisation. Formula: 6.43 + 9.57 x ln(Cr) + 3.78 x ln(Tbili) + 11.2 x ln(INR). MELD >= 15 favours transplant over medical management.

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Frequently Asked Questions

How is MELD score calculated?

What MELD score predicts 90-day mortality?

What is the difference between MELD and MELD-Na?