What are the MGFA classification classes?

Class I: ocular only; Class II: mild generalized (IIa predominantly limb/axial, IIb predominantly bulbar); Class III: moderate generalized; Class IV: severe generalized; Class V: intubation required (myasthenic crisis). Post-intervention status (PR, MM, CSR) also standardized by MGFA.

When is thymectomy indicated in myasthenia gravis?

Thymectomy is indicated for: thymoma (all ages), non-thymomatous generalized AChR-Ab+ MG ages 18–65 (MGTX trial showed benefit), and may be considered in AChR-Ab+ ocular MG. Not indicated for MuSK-Ab+ or seronegative MG outside clinical trials.

Myasthenia Gravis MGFA Classification

Apply MGFA clinical classification (Classes I–V) for myasthenia gravis to stratify disease severity from ocular-only to myasthenic crisis requiring ventilatory support.

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Myasthenia Gravis MGFA Classification

Frequently Asked Questions

What are the MGFA classification classes?

When is thymectomy indicated in myasthenia gravis?