What are TNMB stages for mycosis fungoides?

Stage IA: T1( =10% BSA patches)N0M0B0. Stage IIA: T1-2N1-2M0B0-1. Stage IIB: T3(tumors)N0-2. Stage III: T4(erythroderma). Stage IVA1-2: nodal/blood involvement. Stage IVB: visceral metastasis.

What treatments are used for early-stage mycosis fungoides?

Stage IA-IIA (skin-limited): skin-directed therapies (potent topical steroids, topical nitrogen mustard, narrowband UVB, PUVA, localized RT). TSEBT (total skin electron beam therapy) for widespread plaque/tumor disease.

What systemic therapies are used for advanced MF?

Brentuximab vedotin (anti-CD30) for CD30+ CTCL (Stage IIB+). Mogamulizumab (anti-CCR4) for mycosis fungoides and Sezary syndrome. HDAC inhibitors (vorinostat, romidepsin) for refractory disease. Allogenic SCT for eligible patients.

Mycosis Fungoides TNMB Staging

Stage mycosis fungoides using TNMB classification. Stage IA (T1N0M0B0) carries 95% 10-year survival; Stage IV (T4/N3/M1/B2) carries <20% 5-year survival.

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Mycosis Fungoides TNMB Staging

Frequently Asked Questions

What are TNMB stages for mycosis fungoides?

What treatments are used for early-stage mycosis fungoides?

What systemic therapies are used for advanced MF?