Niemann-Pick Type C Suspicion Score

Calculate the NPC suspicion score using clinical features including vertical supranuclear gaze palsy, gelastic cataplexy, ataxia, and cognitive decline to identify patients needing workup.

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Clinical Guidance

BMI is a screening measure of body size, not a direct measure of body fat. The standard WHO categories are underweight (<18.5), normal (18.5–24.9), overweight (25–29.9), and obese (≥30).

BMI can overestimate body fat in athletes with high muscle mass and underestimate it in older adults with low muscle mass. Interpret it alongside waist circumference and clinical context rather than as a standalone diagnosis.

⚕ Clinical Disclaimer: These calculators are for educational and reference purposes only. Always verify results with qualified clinical judgment and current clinical guidelines. Do not use as a sole basis for medical decisions.
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How It Works

Calculate the NPC suspicion score using clinical features including vertical supranuclear gaze palsy, gelastic cataplexy, ataxia, and cognitive decline to identify patients needing workup

Each component has a specific meaning:

  • Clinical features including vertical supranuclear gaze palsy — The clinical features including vertical supranuclear gaze palsy recorded for the scenario being assessed.
  • Gelastic cataplexy — The gelastic cataplexy recorded for the scenario being assessed.
  • Ataxia — The ataxia recorded for the scenario being assessed.
  • Cognitive decline — The cognitive decline recorded for the scenario being assessed.

Note: Interpret the npc suspicion score result against the thresholds and context described above.

How to Use

Enter the clinical features including vertical supranuclear gaze palsy, gelastic cataplexy, ataxia, cognitive decline for the scenario you are assessing. Calculate the NPC suspicion score using clinical features including vertical supranuclear gaze palsy, gelastic cataplexy, ataxia, and cognitive decline to identify patients needing workup. Use the npc suspicion score result to inform your calculation.

Frequently Asked Questions