Neuromyelitis Optica AQP4 Antibody Probability

Estimate probability of AQP4-IgG seropositivity in suspected NMOSD based on clinical phenotype: optic neuritis, transverse myelitis, area postrema syndrome, and area involvement patterns.

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Clinical Guidance

BMI is a screening measure of body size, not a direct measure of body fat. The standard WHO categories are underweight (<18.5), normal (18.5–24.9), overweight (25–29.9), and obese (≥30).

BMI can overestimate body fat in athletes with high muscle mass and underestimate it in older adults with low muscle mass. Interpret it alongside waist circumference and clinical context rather than as a standalone diagnosis.

⚕ Clinical Disclaimer: These calculators are for educational and reference purposes only. Always verify results with qualified clinical judgment and current clinical guidelines. Do not use as a sole basis for medical decisions.
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How It Works

Estimate probability of AQP4-IgG seropositivity in suspected NMOSD based on clinical phenotype: optic neuritis, transverse myelitis, area postrema syndrome, and area involvement patterns

Each component has a specific meaning:

  • Clinical phenotype: optic neuritis — The clinical phenotype: optic neuritis recorded for the scenario being assessed.
  • Transverse myelitis — The transverse myelitis recorded for the scenario being assessed.
  • Area postrema syndrome — The area postrema syndrome recorded for the scenario being assessed.
  • Area involvement patterns — The area involvement patterns recorded for the scenario being assessed.

Note: Interpret the nmosd aqp4 probability result against the thresholds and context described above.

How to Use

Enter the clinical phenotype: optic neuritis, transverse myelitis, area postrema syndrome, area involvement patterns for the scenario you are assessing. Estimate probability of AQP4-IgG seropositivity in suspected NMOSD based on clinical phenotype: optic neuritis, transverse myelitis, area postrema syndrome, and area involvement patterns. Use the nmosd aqp4 probability result to inform your calculation.

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