What does the Lue classification assess?

Lue classification: Group A (simple curvature, good erection, no deformity): plication. Group B (good erection, significant deformity, indentation, loss of length): grafting. Group C (ED with Peyronie's): penile prosthesis with manual modeling or plaque incision.

When is collagenase considered in Peyronie's?

Collagenase clostridium histolyticum (Xiaflex) FDA-approved for stable Peyronie's (>12 months), curvature 30-90 degrees, palpable plaque, and IIEF >=17. Reduces curvature ~17 degrees over 5 injection cycles.

What is the natural history of Peyronie's?

Active phase (pain, changing deformity, 6-18 months) then stable phase. Spontaneous resolution in only 5-10%. ED develops in 20-40%. Surgical correction deferred until deformity stable >=3-6 months.

Peyronie's Disease Lue Classification

Classify Peyronie's disease using Lue/Jordan classification by plaque characteristics and deformity type to guide surgical approach: plication vs grafting vs prosthesis.

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Peyronie's Disease Lue Classification

Frequently Asked Questions

What does the Lue classification assess?

When is collagenase considered in Peyronie's?

What is the natural history of Peyronie's?