What are high-risk PDR characteristics from DRS?

DRS high-risk PDR characteristics (any one of): (1) vitreous or preretinal hemorrhage, (2) NVD of any amount if vitreous hemorrhage, (3) NVD >=1/4 disc area with or without hemorrhage, (4) NVE >=1/2 disc area with vitreous/preretinal hemorrhage.

When does traction retinal detachment occur in PDR?

Fibrovascular membrane contraction in PDR causes traction retinal detachment (TRD). TRD involving macula requires urgent vitreoretinal surgery. TRD not involving macula may be monitored closely but surgery is indicated if macula threatens.

What is the prognosis of high-risk PDR without treatment?

DRS: 5-year severe visual loss (SVL) risk for high-risk PDR without treatment was 26-37%. PRP reduced SVL risk by >50%. DRCR Protocol S: anti-VEGF ranibizumab was non-inferior to PRP with better DME outcomes.

Proliferative DR High-Risk Characteristics

Identify high-risk proliferative diabetic retinopathy (PDR) characteristics from DRS and ETDRS: NVD >=1/4 disc area OR any NVD with vitreous hemorrhage OR NVE >=1/2 disc area with vitreous hemorrhage.

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DR ETDRS Severity

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Proliferative DR High-Risk Characteristics

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Frequently Asked Questions

What are high-risk PDR characteristics from DRS?

When does traction retinal detachment occur in PDR?

What is the prognosis of high-risk PDR without treatment?