What oxygenation improvement is expected with prone positioning?

PROSEVA trial: prone positioning for >=16h/day in P/F <150 mmHg reduced 28-day mortality 50% (16% vs 32.8%). Oxygenation response: P/F typically improves 50 to 100 mmHg within 1 hour of proning. Non-responders (P/F improvement <20 mmHg): may have dorsal atelectasis pattern or consolidation not amenable to proning.

Who are candidates for prone positioning in ARDS?

Indications: P/F =5 cmH2O and FiO2 >=0.6, Berlin moderate-severe ARDS, optimal supine ventilation for >12 to 24 hours. Contraindications: unstable spine/pelvis fracture, facial fracture, hemodynamic instability, abdominal compartment syndrome, increased ICP, recent sternotomy ( =16h/session.

Prone Positioning Oxygenation Improvement Calculator

Calculate expected PaO2/FiO2 ratio improvement and predict prone positioning response in moderate-severe ARDS using pre-prone P/F ratio and initial oxygenation response at 1 hour of proning.

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Frequently Asked Questions

What oxygenation improvement is expected with prone positioning?

Who are candidates for prone positioning in ARDS?