What TOF ratio defines adequate recovery from rocuronium?

TOF ratio =0.9 (4 equal twitches): adequate recovery. Quantitative TOF monitoring (not subjective tactile fade assessment) is required for reliable determination. Sugammadex 2 mg/kg rapidly reverses moderate block.

How does sugammadex dosing depend on TOF for rocuronium?

Sugammadex: TOF 2 to 4 (T2 present, moderate block): 2 mg/kg. TOF 1 to 2 (deep block, T1 present): 4 mg/kg. Post-tetanic count (PTC) 1 to 2 (profound block): 16 mg/kg. Immediate reversal of rocuronium 1.2 mg/kg: 16 mg/kg. Sugammadex cyclodextrin complex encapsulates steroidal NMB agents (rocuronium, vecuronium) but NOT benzylisoquinolines.

Rocuronium TOF Ratio Assessment

Assess rocuronium train-of-four (TOF) ratio to determine adequacy of reversal and residual neuromuscular blockade risk. TOF ratio <0.9 indicates clinically significant residual blockade.

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Frequently Asked Questions

What TOF ratio defines adequate recovery from rocuronium?

How does sugammadex dosing depend on TOF for rocuronium?