Rosuvastatin ABCG2 Transporter Effect Calculator

Estimate rosuvastatin AUC increase from ABCG2 421C>A variant. Homozygous AA genotype doubles rosuvastatin exposure.

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Clinical Guidance

BMI is a screening measure of body size, not a direct measure of body fat. The standard WHO categories are underweight (<18.5), normal (18.5–24.9), overweight (25–29.9), and obese (≥30).

BMI can overestimate body fat in athletes with high muscle mass and underestimate it in older adults with low muscle mass. Interpret it alongside waist circumference and clinical context rather than as a standalone diagnosis.

⚕ Clinical Disclaimer: These calculators are for educational and reference purposes only. Always verify results with qualified clinical judgment and current clinical guidelines. Do not use as a sole basis for medical decisions.
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How It Works

Estimate rosuvastatin AUC increase from ABCG2 421C>A variant. Homozygous AA genotype doubles rosuvastatin exposure

Each component has a specific meaning:

  • ABCG2 421C>A variant — The abcg2 421c>a variant recorded for the scenario being assessed.

Note: Interpret the rosuvastatin abcg2 result against the thresholds and context described above.

How to Use

Enter the ABCG2 421C>A variant for the scenario you are assessing. Estimate rosuvastatin AUC increase from ABCG2 421C>A variant. Homozygous AA genotype doubles rosuvastatin exposure. Use the rosuvastatin abcg2 result to inform your calculation.

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