How fast should hyponatremia be corrected?

Chronic hyponatremia: correct ≤8-10 mEq/L per 24h to prevent osmotic demyelination syndrome (ODS). Acute (<48h): can correct 1-2 mEq/L/h initially.

What is osmotic demyelination syndrome?

ODS (formerly central pontine myelinolysis) occurs from overly rapid correction of chronic hyponatremia, causing irreversible brainstem demyelination.

Which IV fluid corrects hyponatremia?

3% hypertonic saline (513 mEq/L) for acute symptomatic hyponatremia. Normal saline (154 mEq/L) for depletion-type hyponatremia after assessing SIADH vs hypovolemia.

Sodium Deficit Calculator

Calculate total body sodium deficit for hyponatremia correction (Na deficit = 0.6 × weight × (target Na - actual Na)).

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Frequently Asked Questions

How fast should hyponatremia be corrected?

What is osmotic demyelination syndrome?

Which IV fluid corrects hyponatremia?