Thiopurine TPMT Toxicity Myelosuppression Calculator

Predict azathioprine and 6-mercaptopurine myelosuppression severity from TPMT enzyme activity phenotype.

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Clinical Guidance

BMI is a screening measure of body size, not a direct measure of body fat. The standard WHO categories are underweight (<18.5), normal (18.5–24.9), overweight (25–29.9), and obese (≥30).

BMI can overestimate body fat in athletes with high muscle mass and underestimate it in older adults with low muscle mass. Interpret it alongside waist circumference and clinical context rather than as a standalone diagnosis.

⚕ Clinical Disclaimer: These calculators are for educational and reference purposes only. Always verify results with qualified clinical judgment and current clinical guidelines. Do not use as a sole basis for medical decisions.
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How It Works

Predict azathioprine and 6-mercaptopurine myelosuppression severity from TPMT enzyme activity phenotype

Each component has a specific meaning:

  • TPMT enzyme activity phenotype — The tpmt enzyme activity phenotype recorded for the scenario being assessed.

Note: Interpret the thiopurine tpmt result against the thresholds and context described above.

How to Use

Enter the TPMT enzyme activity phenotype for the scenario you are assessing. Predict azathioprine and 6-mercaptopurine myelosuppression severity from TPMT enzyme activity phenotype. Use the thiopurine tpmt result to inform your calculation.

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Frequently Asked Questions